Ion Mobility-Mass Spectrometry of Protonated Molecules―Intramolecular Proton Transfer by Bimolecular Reaction―

Detection heart failures (HF) biomarkers by proton transfer reaction - mass spectrometry and ion mobility spectrometry

Exhaled breath contains 1% of volatile organic compounds. The concentration of individual biomarkers in hundreds of volatile organic compounds lies within the range ppmppb. In compare with control group the concentrations of acetone, acetic acid, ethanol, propylene biomarkers is significantly higher in HF-PEF group.

Proton-transfer reaction mass spectrometry.

Proton-transfer reaction mass spectrometry (PTR-MS) is a technique developed almost exclusively for the detection of gaseous organic compounds in air. Volatile organic compounds (VOCs) in air have both natural and anthropogenic sources. Natural sources include the emission of organic gases by living objects, both plants and animals. A well-known example, which is discussed later in this review,...

Increased sensitivity in proton transfer reaction mass spectrometry by incorporation of a radio frequency ion funnel.

A drift tube capable of simultaneously functioning as an ion funnel is demonstrated in proton transfer reaction mass spectrometry (PTR-MS) for the first time. The ion funnel enables a much higher proportion of ions to exit the drift tube and enter the mass spectrometer than would otherwise be the case. An increase in the detection sensitivity for volatile organic compounds of between 1 and 2 or...

Ion Mobility Mass Spectrometry

for more complex analysers for automated sample processing and plant control. The separation time will continue to decrease; in the past there has been limited interest in fast separations but this could change as automated sample processing is developed. Increasing use of coupled techniques such as GC-GC, liquid chromatography-GC, and supercritical Suid chromatography-GC for the separation of ...

Ion Mobility-Mass Spectrometry